
Eavesdrop on the EV “surfeome”
Take advantage of powerful LC/MS proteomics approaches to study the biology of surface-associated extracellular vesicle (EV) proteins (the surfeome) and to identify EV surface biomarkers using SBI’s ExoMSTM Surface Protein Capture Kit (Serum/Plasma). The kit provides a fast, well-validated, and robust method for selectively capturing surface and membrane-associated proteins from EVs that have already been isolated from serum or plasma, enabling proteomics studies of this important subset of EV proteins. Because of the low residual protein carryover delivered by this kit, you get increased detection of low-abundance biomarkers that are often missed using traditional approaches.
Ensure that your exosomes are telling you everything with SBI’s ExoMSTM Surface Protein Capture Kit (Serum/Plasma).
- Unique—the only commercially available kit that specifically captures exosome surface and membrane proteins
- Sensitive—removes many common contaminants from EV preps, such as albumin and IgG, for improved biomarker detection by LC/MS
- Compatible—works with EVs isolated using a variety of methods including ExoQuick®, ExoQuick® PLUS, ultracentrifugation, and most column-based kits sold by other vendors
- Fast—go from isolated sample to LC/MS in less than 5 hours
- Flexible—choose this kit for exosomes isolated from serum or plasma, the ExoMS Surface Protein Capture Kit (Tissue Culture) for exosomes isolated from tissue culture or other biofluids, or the ExoMS Total Protein Capture Kit to isolate all EV proteins from exosomes isolated from any biofluid